Cruciferous vegetable intake and cancer prevention: role of nutrigenetics.
نویسندگان
چکیده
Five-Year Efficacy and Safety Analysis of the Adenoma Prevention with Celecoxib Trial. Monica M. Bertagnolli, Craig J. Eagle, Ann G. Zauber, Mark Redston, Aurora Breazna, KyungMann Kim, Jie Tang, Rebecca B. Rosenstein, Asad Umar, Donya Bagheri, Neal T. Collins, John Burn, Daniel C. Chung, Thomas Dewar, T. Raymond Foley, Neville Hoffman, Finlay Macrae, Ronald E. Pruitt, John R. Saltzman, Bruce Salzberg, Thomas Sylwestrowicz, Ernest T. Hawk and for the Adenoma Prevention with Celecoxib Study Investigators ............................................................310
منابع مشابه
Cruciferous vegetable consumption and lung cancer risk: a systematic review.
BACKGROUND Cruciferous vegetables, rich in isothiocyanates, may protect against lung cancer. Glutathione S-transferases are important in metabolizing isothiocyanates; hence, variants in GST genes may modify the association between cruciferous vegetable intake and lung cancer. We carried out a systematic review to characterize the association between cruciferous vegetable intake and lung cancer ...
متن کاملGSTP1 and GSTA1 polymorphisms interact with cruciferous vegetable intake in colorectal adenoma risk.
The possible interplay between cruciferous vegetable consumption, functional genetic variations in glutathione S-transferases (GST) M1, T1, P1, and A1, and colorectal adenomas, was investigated in a Dutch case-control study. The GSTM1 and GSTT1 deletion polymorphisms, and the single nucleotide polymorphisms in GSTP1 (A313G) and in GSTA1 (C-69T) were assessed among 746 cases who developed colore...
متن کاملPostdiagnosis cruciferous vegetable consumption and breast cancer outcomes: a report from the After Breast Cancer Pooling Project.
Cruciferous vegetables are a major source of glucosinolate-derived bioactive compounds such as isothiocyanates, which have been shown in animal and in vitro studies to inhibit cancer growth and progression. Few studies have investigated cruciferous vegetable intake after diagnosis and breast cancer outcomes. Using data from the After Breast Cancer Pooling Project, which includes prospective dat...
متن کاملIntake of cruciferous vegetables modifies bladder cancer survival.
BACKGROUND Intake of cruciferous vegetables, a rich source of dietary isothiocyanates, has been inversely associated with risk of bladder cancer. Due to the potent antiproliferative effects of dietary isothiocyanates on bladder cancer in in vitro and in vivo models, cruciferous vegetable intake may also play a role in survival among patients with bladder cancer. METHODS Using information obta...
متن کاملConsumption of raw cruciferous vegetables is inversely associated with bladder cancer risk.
Cruciferous vegetables contain isothiocyanates, which show potent chemopreventive activity against bladder cancer in both in vitro and in vivo studies. However, previous epidemiologic studies investigating cruciferous vegetable intake and bladder cancer risk have been inconsistent. Cooking can substantially reduce or destroy isothiocyanates, and could account for study inconsistencies. In this ...
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عنوان ژورنال:
- Cancer prevention research
دوره 2 4 شماره
صفحات -
تاریخ انتشار 2009